Ammar Yahya  Kadhim Almamoori,Gihan Hosny  Abd Elsamie,Metwally Aly Metwally,Samir  Ali ,
Sono and photo stimulated Chlorine E6 nanocomposite in tumor-bearing mice: upcoming cancer treatment
Radiology and Medical Diagnostic Imaging
2019
2613-7836
http://dx.doi.org/10.31487/j.RDI.2019.03.04
https://www.sciencerepository.org/sono-and-photo-stimulated-chlorine-e6-nanocomposite-in-tumor-bearing-mice-upcoming-cancer-treatment_RDI-2019-3-104 
Abstract: This study was directed at study the effectiveness of cancer targeted therapy using the activated
Chlorine E6 nanocomposite (Nano-CE6). Study was applied on male Swiss albino mice, implanted with
Ehrlich tumor (EAC) divided into six groups. Two energy sources were used; laser and Ultrasound. Results
showed that Nano-CE6 is a potential sensitizer for photodynamic or sonodynamic treatment of tumor. NanoCE6 plays an important role in tumor growth inhibition and cell death induction. Activated Nano-CE6 with
both infrared laser and ultrasound has a potential antitumor effect. The results indicated that (FA–NGO–
CE6) could be used as a unique nanocomposite for cancer targeted therapy SPDT.
Keywords: Nano-Chlorine E6, ehrlich tumor, sonodynamic therapy, photodynamic therapy