Prasanna N. de Silva,
Can Repurposed Polyvalent Vaccine Boosters (like BCG) Limit Dementia Progression by Modifying Microglial Activation Phenotypes?
Neurology and Neurobiology
2020
2613-7828
http://dx.doi.org/10.31487/j.NNB.2020.03.08
https://www.sciencerepository.org/can-repurposed-polyvalent-vaccine-boosters-like-bcg-limit-dementia_NNB-2020-3-108 
Abstract: This article sets out a case for considering generally available polyvalent vaccines such as BCG, MMR and
DPT to be repurposed for treating emerging cognitive decline in elderly people through reducing
neuroinflammation via microglial activation. Up to now, treatments to reduce parenchymal oligomers such
as Amyloid beta in Alzheimer’s disease have been clinically unsuccessful. Therefore, an alternative
approach to try and directly attenuate microglial activation has utility.Keywords: Polyvalent vaccines, microglial activation, neurodegenerative disease