Qiliang Yin,Shijie Lan,Fengming Jiang,Di Wu, Renal Pelvis and Renal Calices Sarcomatoid Carcinoma: A Case Report Journal of Surgical Oncology 2020 2674-3000 http://dx.doi.org/10.31487/j.JSO.2020.05.01 https://www.sciencerepository.org/renal-pelvis-and-renal-calices-sarcomatoid-carcinoma_JSO-2020-5-101 Abstract: Introduction: Sarcomatoid carcinoma is one of the malignant neoplasms characterized by the ability to differentiate into both epithelial tissue and mesenchymal tissue. And it is rare in urinary system with a high degree of malignancy and prognosis is poor. Patient Concerns: The present article reports a 63-year-old man presented with recurrent left flank pain for two years. Radiological tests suggested a space-occupying lesion in left kidney with enlarged paranephric /retroperitoneal lymph nodes. Diagnosis: The pathological diagnosis following left nephrectomy indicated renal pelvis and renal calices sarcomatoid carcinoma; pTNM: T4N0M0. Interventions: No radiotherapy or chemotherapy were performed after the surgery and underwent rapid growth. Outcomes: The patients died six months later. Conclusion: Renal pelvis and renal calices sarcomatoid carcinomas is a highly malignant tumor and difficult to diagnose at its early stage. Definite diagnosis relies on the combination of immunohistochemistry (IHC) and morphological analyses and there currently is no effective treatment.Keywords: Sarcomatoid carcinoma, Renal pelvis, renal calices, immunohistochemistry, treatment