Ze Zhang,Hao Wu,Shenglin Gao,Jiasheng Chen,Chao Lu,Weijiang Mao,Xingyu Wu,Tianle Cheng,Lifeng Zhang,Li Zuo, Evaluation of the Effects of Silver Nitrate Renal Pelvic Instillation and Retroperitoneoscopic Renal Pedicle Lymphatic Disconnection for Chyluria Journal of Surgical Oncology 2020 2674-3000 http://dx.doi.org/10.31487/j.JSO.2020.04.09 https://www.sciencerepository.org/evaluation-of-the-effects-of-silver-nitrate-renal-pelvic-instillation_JSO-2020-4-109 Abstract: Introduction: In this study, the efficacy, advantages, and disadvantages of transurethral cystoscopic silver nitrate renal pelvic instillation and retroperitoneoscopic renal pedicle lymphatic disconnection for chyluria were compared to provide a clinical reference. Methods: Forty patients with chyluria who were admitted to our hospital between June 2007 and June 2017 were selected as the research subjects and divided into two groups. The patients in group A (n=25) were treated with transurethral cystoscopic silver nitrate renal pelvic instillation regimen, while those in group B (n=15) were treated by retroperitoneoscopic renal pedicle lymphatic disconnection. Operative time, intraoperative blood loss volume, length of postoperative hospital stay, cure rate, complication rate and recurrence rate were compared between the two groups. Results: All the 40 patients were successfully treated. Group B had a higher cure rate, lower complication rate and lower recurrence rate than in group A, the differences were statistically significant (P < 0.05). But group A had a shorter length of hospital stay and less surgical trauma, the differences were statistically significant (P < 0.05). Conclusion: Retroperitoneoscopic renal pedicle lymphatic disconnection for chyluria can be used as one of the first choices of treatment for chyluria. Although the recurrence rate with transurethral cystoscopic silver nitrate renal pelvic instillation is high, the treatment can be administered again when the disease recurs. At the same time, it is less invasive to the patients and they are more receptive.Keywords: Chyluria, renal pedicle lymphatic disconnection, renal pelvic instillation sclerotherapy