Humaid Al Farii,Marc-Antoine  Ricard,Motaz  AlAqeel,Robert  Turcotte,Sungmi  Jung ,
Dedifferentiated Chondrosarcoma with Epithelial Differentiation: A Case Report and Review of the Literature
Journal of Surgical Oncology
2020
2674-3000
http://dx.doi.org/10.31487/j.JSO.2020.02.08
https://www.sciencerepository.org/dedifferentiated-chondrosarcoma-with-epithelial-differentiation_JSO-2020-2-108 
Abstract: Case: We describe a case of 72-year-old male with dedifferentiated chondrosarcoma with osteosarcomatous
and epithelioid (squamous) dedifferentiation. As first described in the literature by Dahlin and Beabout, a
well-differentiated benign chondral lesion abruptly juxtaposed to a high-grade non-cartilaginous component
is the classical definition of a chondrosarcoma [1]. The non-cartilaginous component is typically an
osteosarcoma, fibrosarcoma or malignant fibrous histiocytoma with rare instances of leiomyosarcoma, giant
cell tumor and rhabdomyosarcoma [2].
Conclusion: We report our rare instance of squamous dedifferentiation of a dedifferentiated
chondrosarcoma along with other five cases that have been reported so far in the literatureKeywords: Dedifferentiated chondrosarcoma, epithelial dedifferentiation