Sebastião Hetem,Celina Antônio Prata,Marlei Seccani Galassi,Lizeti Toledo Oliveira Ramalho,Hermes Pretel, Evidence of Dental Lamina Preservation in the Development of Mice First Molars Dental Oral Biology and Craniofacial Research 2021 2613-4950 http://dx.doi.org/10.31487/j.DOBCR.2021.01.01 https://www.sciencerepository.org/evidence-of-dental-lamina-preservation-in-the-development-of-mice_DOBCR-2021-1-101 Abstract: The aim of this work was to analyse the behaviour of the dental lamina during the development process of first molar teeth. The offspring of female mice were analysed at the 16th day of intra-uterine life and since birth till 17 days old with the aim to evaluate the dental lamina evolution of upper and lower first molars. The animals were sacrificed, and the heads embedded in paraffin in order to get frontal or sagittal sections whose were stained by hematoxylin and eosin method. The results showed a very clear presence of the dental lamina in all periods under analysis, without the occurrence of its disorganization, in other words, it was permanently connecting the developing tooth germ to the oral epithelium until advanced dental eruption.Keywords: Dental lamina, tooth development, mice