Eudoxie Pepelassi,Harry Charalabos Stamatakis,Ioannis Vrotsos,Nikolaos Markou,Sotirios Kotsovilis,
The Use of Platelet-Rich Plasma Alone in The Treatment of Periodontal Endosseous Defects: A Report of Two Clinical Cases
Dental Oral Biology and Craniofacial Research
2019
2613-4950
http://dx.doi.org/10.31487/j.DOBCR.2019.04.02
https://www.sciencerepository.org/the-use-of-platelet-rich-plasma-alone-in-the-treatment-of-periodontal-endosseous-defects-a-report-of-two-clinical-cases_DOBCR-2019-4-102 
Abstract: Background: On the basis of animal histologic data and randomized controlled trials, the authors provide
reports of two cases, in which platelet-rich plasma (PRP) alone was used to treat periodontal endosseous
defects in patients exhibiting generalized severe chronic periodontitis.
Case Descriptions: Clinicians treated endosseous defects with a probing pocket depth of 6 and 8
millimeters (case 1), and 4 mm (case 2) by using PRP alone. At six months, complete periodontal pocket
resolution, and significant clinical attachment gain and radiographic defect fill, compared with pre-surgical
values, occurred in all defects.
Clinical Implications: PRP alone may be clinically and radiographically efficacious in the treatment of
periodontal endosseous defects.Keywords: Periodontitis, periodontal treatment, monotherapy, periodontal endosseous defects, platelet-rich plasma