Katsuhiro  Makino,Taketo  Kawai,Yusuke  Sato,Naohiro  Makise,Takeru  Morishige,Takahiro  Oshina,Yoshiyuki  Akiyama,Yuta  Yamada,Masaki  Nakamura,Daisuke  Yamada,Motofumi  Suzuki,Tetsuo  Ushiku,Haruki  Kume,
Implantation of Colorectal Cancer from the Upper Urinary Tract to the Bladder via Urine
Clinical Oncology and Research
2020
2613-4942
http://dx.doi.org/10.31487/j.COR.2020.08.22
https://www.sciencerepository.org/implantation-of-colorectal-cancer-from-the-upper-urinary-tract-to_COR-2020-8-122 
Abstract: Although the implantation of urothelial carcinoma from the upper urinary tract to the bladder occurs
frequently, the involvement of cancers of other histologic types is rare. Here, we present an unusual case of
intravesical recurrence, following ureteral invasion, by colorectal cancer. A 69-year-old woman developed
a local recurrence of colorectal cancer involving the sigmoid colon and left ureter. The patient underwent a
sigmoidectomy and left nephroureterectomy. Six months later, bladder tumors were observed, and a
transurethral resection was performed. Histological examination of the bladder tumors revealed
adenocarcinoma consistent with the findings of the colorectal cancer that had been previously resected. The
most probable mechanism of intravesical recurrence would be the implantation of colorectal cancer cells
from the upper urinary tract to the bladder via urine.Keywords: Implantation, colorectal cancer, adenocarcinoma, ureteral invasion, intravesical recurrence