Aisoni F ,Bonazza S ,Carcoforo P ,D’Urbano F ,Fabbri Nicolò,Pedriali M ,Soliani G ,
Metastatic Anal Lesion of Primary Lobular Breast Carcinoma- An Insidious, Rare and Subclinical Progression: Case Report and Review of the Literature
Clinical Oncology and Research
2020
2613-4942
http://dx.doi.org/10.31487/j.COR.2020.03.12
https://www.sciencerepository.org/metastatic-anal-lesion-of-primary_COR-2020-3-112 
Abstract: Gastrointestinal metastasis from primary breast carcinoma is very uncommon, with less than 1% of breast
carcinomas metastasize to the gastrointestinal tract but anorectal involvement is even rarer. These metastatic
lesions can lead to diagnostic challenge for clinicians as they can mimic primary colo-rectal cancer due to
the lack of diagnostic signs. The increase of patient survival could lead to an unusual late resumption of
metastatic disease, often for a long-time occult. Nowadays, an almost completely absent literature is unable
to suggest diagnostic pathways capable of predicting this type of disease evolution. We present the case of
a 76-year old woman who underwent treatment for an infiltrative lobular carcinoma of the breast who
developed metastasis of the anal canal 11- years later. A literature review was performed.
Keywords: Breast cancer, metastasis, anal canal, case report