James Pandarakalam, Analysis of an Epidemiological Anomaly of COVID-19: Transcultural and Immunological Psychiatry Clinical Microbiology and Research 2021 2674-418X http://dx.doi.org/10.31487/j.CMR.2021.01.01 https://www.sciencerepository.org/analysis-of-an-epidemiological-anomaly-of-covid-19_CMR-2021-1-101 Abstract: Evidence exists for an epidemiological trend of transmission concentrations of COVID-19 within migrant communities from tropical weather conditions. Minority groups are over-represented in hospitalisations and deaths from the virus, and it appears that the observed anomaly may be due to multifactorial causes. Underactive immune responses in cooler temperatures and diminished synthesis of vitamin D, both of which are associated with genetic factors among ethnic minority groups, could help to explain the higher incidence of COVID-19 among ethnic minority communities. Neither factor is specific to a migrant community but common to general populations. The overstatement of contributory genetic factors runs the risk of racial stigmatisation. If environmental factors are given their due importance, individuals belonging to ethnic minorities may try to adopt new ways to combat the pandemic, while overemphasising racial factors would only leave them helpless. The renewed interest of psychiatrists in immunology would support the emerging field of immunopsychiatry. COVID-19 is environmentally sensitive, and all medical specialities, including the mental health profession, should contribute their wisdom to defeating or making a truce with the viral phenomenon.Keywords: Immunity, genetics, compromised immunity, thermal regulations, vitamin D, comorbidity