Abira Datta,Basudev Bhattacharya,Rajib Gon Chowdhury,Siddhartha Chatterjee,Subhankar Chowdhury,
Elevated Level of Serum Vitamin D Reduce the Chance of Latent Genital Tuberculosis
Clinical Microbiology and Research
2019
2674-418X
http://dx.doi.org/10.31487/j.CMR.2019.01.05
https://www.sciencerepository.org/elevated-level-of-serum-vitamin-d-reduce-the-chance-of-latent-genital-tuberculosis_CMR-2019-1-105 
Abstract: Aim: To explore the possibility of risk factor between latent genital tuberculosis with association of low
secretion anti-mullerian hormone(AMH) and low level of Vitamin D for infertility.
Design: Retrospective study was done in the reproductive medicine unit of Calcutta Fertility Mission,
Kolkata-700019, and India
Result: From January 2017 to January 2019, total 150 Subjects (n= 75 TB-PCR positive and n=75 TB-PCR
negative cases as control) were included in this study on the basis of inclusion and exclusion criteria. We
have found that mean value of AMH and Vitamin D were higher in PCR negative group than positive group.
Various level of AMH and Vitamin D concentration for PCR positive and negative cases were statistically
significant (p-value < 0.01).
Conclusion: Our finding is that vitamin D deficiency is highly prevalent not only in active tuberculosis but
also in latent genital tuberculosis subjects and serum Vitamin D level may help in treatment of latent genital
tuberculosis. Elevated level of Vitamin D in serum may rule out latent tuberculosis.Keywords: Latent genital tuberculosis, anti-mullerian hormone, polymerase chain reaction, in vitro fertilization, cholecalciferol, to 25 hydroxyvitamin D, 1,25-dihydroxyvitamin D, Mycobacterium tuberculosis, DNA, chemiluminescence immunoassay