Adel  El-Badrawy,Ahmed  Tawfik,Gehad  Saleh,Mai  Abdel-Naby,Hayam  Ghazy,Ziad  Emarah,Ahmed  Ramez,Mohamed  A. Elfatah,Ahmed  Eltantawy,Mona   M. Taalab,Noha  Eisa,Shaimaa  El-Ashwah,Yasmine  Essam,Basma  Atef,Shahira Ali  El-Etreby,Monir  H. Bahgat,Ahmed  Deiab,Hatem  Elalfy,Tarek  Besheer,Ahmed  El-Mesery,Mohamed  Mahmoud Sarhan,Suzy  Abd Elmabood,Ahmed  Megahed,Mohamed  Farouk Akl,Khaled  Abouelkhair,Hanan  Wahba,Amal  Halim,Nirmeen  Megahed,Eman  Omar Khashaba,
MDCT Evaluation of Hepatic Manifestations in Malignant Hematological Disorders
Cardiovascular Disorder and Medicine
2020

http://dx.doi.org/10.31487/j.CDM.2020.02.01
https://www.sciencerepository.org/mdct-evaluation-of-hepatic-manifestations-in-malignant-hematological-disorders_CDM-2020-2-101 
Abstract: Objective: The aim of this work was to evaluate Multidetector Computed Tomography (MDCT) findings
of hepatic manifestation in common malignant hematological disorders.
Materials and Methods: This retrospective study included 300 patients with different types of malignant
hematological disorders. They were 119 female and 181 male (mean age, 45.4 year; range, 5-70 years). The
most common hematological disorder was Non-Hodgkin lymphoma (NHL) detected in 192/300 (64%)
patients and then Hodgkin disease (HD) detected in 40/300 (13.3%) patients. All 300 patients had
ultrasonography. Clinical evaluation and laboratory assessment were done for all patients. Whole body and
triphasic abdominal CT scanning was performed on 64 MDCT systems.
Results: MDCT scanning revealed hepatic affection in 82/192 of NHL. All these 82 cases revealed
hepatomegaly and focal lesion detected in 36 cases. As regard Hodgkin disease (HD), hepatomegaly
detected in 22/40 cases and focal lesion detected in 8/40 cases. Hepatomegaly detected in 8/14 cases of
acute myeloid leukemia (AML) and focal lesion detected in 4/14 cases. In cases of chronic lymphocytic
leukemia (CLL), hepatomegaly detected in 6/22 cases with no detection of focal lesion.
Conclusion: Hepatic involvement is often observed in several malignant hematological disorders, resulting
in abnormalities in liver imaging studies. Malignant hematological disorders must be considered in
hepatomegaly and hepatic focal lesions either single or multiple. MDCT is the diagnostic modality of choice
for diagnosis and follow up of liver affection in different malignant hematological disorders.Keywords: Liver, hematological malignancies, computed tomography