Taoufik Abdellaoui,Soukaina  Belfaiza,Yassine  Malek,Fouad  Elasri,Karim  Reda,Abdelbarre  Oubaaz,
Large Orbital Tumor in a Patient with Neurofibromatosis Type 2
American Journal of Surgical Case Reports
2020
2674-5046
http://dx.doi.org/10.31487/j.AJSCR.2020.03.11
https://www.sciencerepository.org/large-orbital-tumor-in-a-patient-with-neurofibromatosis-type-2_AJSCR-2020-3-111 
Abstract: Neurofibromatosis type 2 (NF2) is a separate entity from Neurofibromatosis type 1 (NF1) or von
Recklinghausen’s disease, and is much less frequent than NF1. Vestibular schwannomas are the hallmark
lesion, affecting 95% of individuals and typically occur bilaterally. Schwannomas commonly occur on other
nerves intracranially and in the spinal compartment, along with meningiomas, ependymomas, and gliomas.
Ophthalmologic abnormalities are present in the majority of NF2 patients, including cataracts, retinal
changes, optic nerve sheath meningiomas and other optic pathway tumors. These tumors are sometimes
large and can induce significant proptosis. We report the case of a large orbital meningioma responsible for
severe proptosis in a patient with NF2.Keywords: Neurofibromatosis, type 2, tumor, schwannoma, meningioma, proptosis