TY - JOUR
AR - JSO-2020-6-102
TI - Effectiveness of the Nipples-Saving Mastectomy (NSM): Review on the Results, Oncologic Safety and Surgical Complications
AU - Domenico, Parmeggiani
AU - Mallitti , C
AU -  Lanza , Volpe M
AU - Parisi , S
AU - Rinaldi , S
AU - Nesta , G
AU - Gualtieri , G
AU - Fiorentino , F
AU - Terracciano , GM
AU - Bottino , V
AU - Ruggiero , R
AU - Docimo , L
JO - Journal of Surgical Oncology
PY - 2020
DA - Mon 07, Dec 2020
SN - 2674-3000
DO - http://dx.doi.org/10.31487/j.JSO.2020.06.02
UR - https://www.sciencerepository.org/effectiveness-of-the-nipples-saving-mastectomy-nsm-review-on-the_JSO-2020-6-102 
KW - Breast cancer, nipples-saving mastectomy, oncologic risk, BRCA mutation
AB - Background: The nipples-saving mastectomy (NSM), most recent technique, allows the whole mammary
gland removal preserving the nipple-areola compound (NAC), obtaining oncologic safe results. When
indicated, NSM is validated by the great aesthetic results obtained.
Objectives: The objective of this review is the evaluation of the effectiveness and oncologic safety of the
nipple-saving mastectomy, marking the most frequent complications. Moreover, the possibility to use the
NSM procedure as prophylactic mastectomy in patients at high risk has been evaluated.
Research Methods: A bibliographic research about clinical studies and previous reviews related to nipplessaving mastectomy has been conducted. No limitation about language was performed.
Results: The study included 12 articles, for a total of 2859 patients and 3849 NSM. Patients candidate to
NSM, either as a prophylactic or curative treatment of mammary carcinoma, must undergo a careful
selection screening. Most frequently occurring surgery-related complications were necrosis and infections;
though not altering the cosmetic results, that have been positively evaluated in almost all patients.
Conclusion: Preservation of the areola-nipple compound seems to be oncologically safe and does not
increase local recurrences, compared to the previous techniques. Moreover, it is associated with better
aesthetic results and patients’ higher satisfaction.