TY - JOUR
AR - SCR-2022-7-102
TI - Small Cell Carcinoma of the Breast: A Report of 2 Cases and Literature Review
AU - Paige,  Aiello
AU - Steve, Kim
AU - Lisa, Baek
AU - Lydia, Choi
JO - Surgical Case Reports
PY - 2022
DA - Tue 12, Jul 2022
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2022.07.02
UR - https://www.sciencerepository.org/small-cell-carcinoma_SCR-2022-7-102 
KW - Oncology, breast cancer, surgical oncology, breast surgery
AB - Two female patients were diagnosed with primary small cell carcinoma of the breast that was estrogen receptor, progesterone receptor, and Her-2 Neu negative. Diagnosis was made by ultrasound-guided core needle biopsy. They both underwent neoadjuvant chemotherapy. The first patient had negative sentinel lymph node biopsy and underwent postoperative whole breast radiation. She has remained disease-free. The second patient underwent preoperative radiation only, had one positive sentinel lymph node, and declined postoperative radiation. The second patient had metastasis to the axillary lymph nodes as well as recurrence. She was treated with chemotherapy, surgery, and radiation, but ultimately developed more diffuse metastasis. We discuss current literature regarding diagnosis, treatment, and prognosis in small cell carcinoma of the breast.