TY - JOUR
AR - SCR-2020-12-111
TI - Multiple Synchronous Squamous Cell Cancers of the Skin and Esophagus: Differential Management of Primary Versus Secondary Tumor
AU - Cristians , Gonzalez
AU - Silvana , Perretta
AU - Bernard , Dallemagne
AU - Antonio , D’Urso
AU - Patrick , Pessaux
AU - Didier , Mutter 
JO - Surgical Case Reports
PY - 2020
DA - Tue 15, Dec 2020
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2020.12.11
UR - https://www.sciencerepository.org/multiple-synchronous-squamous-cell-cancers-of-the-skin-and-esophagus_SCR-2020-12-111 
KW -  Double primary tumor, second primary tumor, multiple primary tumor, esophageal cancer, skin cancer, squamous cell cancer
AB - Multiple primary tumors are uncommon in patients with squamous cell esophageal cancer. Conventional
imaging methods have limitations in detecting those tumors. Although 18-F-fluoro-deoxyglucose-positron
emission tomography scanner increases the detection of multiple synchronous tumors in patients with other
malignancies, its contribution in patients with squamous cell esophageal cancer has not been assessed as it
is not systematically performed. The detection of synchronous skin squamous cell tumors in patients with
squamous cell esophageal cancer presents a challenge for making diagnostic and therapeutic decisions. A
metastatic tumor leads to palliative management, whereas the diagnosis of a primary skin tumor requires
curative treatment of both squamous cell tumors. Pathological evaluation appears crucial in the decision.