TY - JOUR
AR - SCR-2019-2-107
TI - Humeral Osteomyelitis with Apophysomyces ossiformis in an Immunocompetent Patient: A Case Report
AU - Andrew J., Watt
AU - Clifford C., Sheckter
AU - Travis J. , Miller
JO - Surgical Case Reports
PY - 2019
DA - Sat 30, Mar 2019
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2019.02.07
UR - https://www.sciencerepository.org/humeral-osteomyelitis-with-apophysomyces-ossiformis-in-an-immunocompetent-patient-a-case-report_SR-SCR-2019-2-107 
KW - Fungal osteomyelitis,  Apophysomyces ossiformis,  limb salvage,  free tissue transfer
AB - Introduction: Osteomyelitis of a limb can lead to devastating functional consequences. Fungal
osteomyelitis is rare in immunocompetent patients, and compared to bacterial osteomyelitis, fungal
infections are more difficult to eradicate.
Case Report: We present a case of a 59-year-old male who suffered traumatic left open radius and ulna
fractures at the elbow with significant soft tissue loss. He underwent spanning fixation across the elbow,
and soft tissue coverage was provided with a free latissimus flap. At the time of flap coverage, the patient
was found to have fungal osteomyelitis with the organism Apophysomyces ossiformis. The patient achieved
wound closure and functional use of the left upper extremity.
Conclusion: The reported case demonstrates the pathogenicity of a microorganism not previously described
in human disease. In this case, treatment was successful with local debridement, placement of antibiotic
beads, and long-term antifungal therapy.