TY - JOUR
AR - SCR-2018-3-126
TI - First case of twin pregnancy after vaginal radical trachelectomy in a Japanese woman
AU - Akari , Kawamata
AU - Masahito , Mizuuchi
AU - Miyuki , Morishita
AU - Shinichi , Ishioka
AU - Takafumi , Kuroda
AU - Tasuku , Mariya
AU - Tsuyoshi , Baba
AU - Tsuyoshi, Saito
AU - Yuko , Mizugaki
AU - Yuya , Fujibe
JO - Surgical Case Reports
PY - 2018
DA - Sun 30, Dec 2018
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2018.03.026
UR - https://www.sciencerepository.org/first-case-of-twin-pregnancy-after-vaginal-radical-trachelectomy-in-a-japanese-woman_SCR-3-126 
KW - Radical trachelectomy, uterine cervical cancer, twin pregnancy
AB - Twin pregnancy after radical trachelectomy (RT) for uterine cervical cancer involves an extremely high risk
of preterm premature rupture of the membrane (pPROM) and the following occurrence of preterm birth.
Herein we report the first case of twin pregnancy after vaginal RT in a Japanese woman. The patient was a
36-year-old nulliparous woman. She became pregnant with twins one year after vaginal RT with
laparoscopic lymphadenectomy and the following treatment with the use of in vitro fertilization/embryo
transfer. Her pregnancy course was favorable with vaginal disinfection, bed rest, and administration of
progesterone, ritodrine, and an ulinastatin vaginal suppository. At 31 weeks + 4 days of pregnancy, a
scheduled cesarean section was performed. One baby weighed 1000g, with Apgar scores of 7/8, and the
other 1100g, with Apgar scores of 8/9. Her postpartum course was also favorable. The mother remains
without evidence of recurrence of the cancer at the time of this report.