TY - JOUR AR - SCR-2018-3-113 TI - The Great Imposture: Eosinophilic Cholangitis AU - Schammel , David AU - Christine , Schammel AU - Krishna , Yamuna AU - Schammel , Joshua AU - Trocha , Steven AU - Young , Allison JO - Surgical Case Reports PY - 2018 DA - Wed 14, Nov 2018 SN - 2613-5965 DO - http://dx.doi.org/10.31487/j.SCR.2018.03.013 UR - https://www.sciencerepository.org/the-great-imposture-eosinophilic-cholangitis_SCR-3-113 KW - biliary obstruction, benign liver disease, cholangiocarcinoma, diagnostic algorithm, malignant versus benign AB - Eosinophilic Cholangitis (EC) is a rare, benign disease often mistaken for cholangiocarcinoma as clinically and radiologically EC resembles cholangiocarcinoma. Often, extensive hepatobiliary resections for a presumed malignancy are completed; however, with appropriate diagnosis EC can be managed medically. We present two cases of EC with a comprehensive literature review and a proposed diagnostic decision algorithm for EC by which to evaluate suspicious lesions with biliary obstruction and potentially avoid surgery for this benign disease.