TY - JOUR
AR - SCR-2018-3-106
TI - Vaccination-induced inflammatory accumulation of axillary lymph nodes detected by FDG-PET in a breast cancer patient
AU - Akiyo , Yoshimura
AU - Ayumi , Kataoka
AU - Haruru , Kotani
AU - Hiroji , Iwata
AU - Junko , Ishigro
AU - Kayoko , Sugino
AU - Madoka , Iwase
AU - Masataka , Sawaki
AU - Masaya , Hattori
AU - Naomi , Gondo
AU - Sakura , Ohnishi
JO - Surgical Case Reports
PY - 2018
DA - Wed 31, Oct 2018
SN - 2613-5965
DO - http://dx.doi.org/10.31487/j.SCR.2018.03.006
UR - https://www.sciencerepository.org/vaccination-induced-inflammatory-accumulation-of-axillary-lymph-nodes-detected-by-FDG-PET-in-a-breast-cancer-patient_SCR-3-106 
KW - Breast cancer, FDG-PET, axilla lymph node, influenza vaccination, false-positive
AB - Evaluation of axilla lymph node metastasis is very important in determining the treatment strategy for
primary breast cancer. The imaging method 2-fluoro-2-deoxy-D-glucose positron emission tomography
(FDG-PET) provides reliable information about metastasis, however it has limitations. A 40-year-old female
first noticed a mass in her left breast. Ultrasonography (US) showed an uncircumscribed mass measuring
1.5 cm beneath the nipple in her left breast, and swelling axilla lymph node as metastasis. Primary tumor
and 4 axilla lymph nodes were detected as hot spot by FDG-PET. However, we got new information which
she received influenza vaccination 4 days before she had undergone FDG-PET before determining the
strategy with patient. To decide the plan of treatment, it was necessary to have the reliable imaging result,
therefore, we performed the second FDG-PET 25 days after the influenza vaccination. We report a case
showing false-positive of axillary lymph nodes by FDG-PET caused by influenza vaccination. Influenza
vaccination before FDG-PET examination may cause axillary lymph node accumulations, especially within
several days after vaccination.