TY - JOUR
AR - JICOA-2020-4-107
TI - Obstructive Sleep Apnea Syndrome in Acute Coronary Syndrome Patients
AU - Dasdemir , Ilkhan Gulay
AU - Hakan , Çelikhisar
JO - Journal of Integrative Cardiology Open Access
PY - 2020
DA - Thu 23, Jul 2020
SN - 2674-2489
DO - http://dx.doi.org/10.31487/j.JICOA.2020.04.07
UR - https://www.sciencerepository.org/obstructive-sleep-apnea-syndrome-in-acute-coronary-syndrome-patients_JICOA-2020-4-107 
KW - Acute coronary syndrome, Berlin questionnaire, Epworth sleepiness score, obstructive sleep apnea syndrome, SYNTAX score
AB - Objective: There is increasing evidence linking obstructive sleep apnea syndrome (OSAS) with
cardiovascular pathogenesis. OSAS diagnostic methodologies have recently come to standards, and there is
not enough in-depth research in the field of sleep medicine and cardiology. In this study, we aimed to
evaluate the presence of OSAS and its relationship with severity of coronary artery disease in patients with
acute coronary syndrome (ACS).
Materials and Methods: 192 patients who applied with acute coronary syndrome and who underwent
coronary angiography were included in the study. 96 patients were ST segment elevation myocardial
infarction (STEMI) and 96 patients were non-ST segment elevation myocardial infarction (NSTEMI).
SYNTAX scores of the patients were calculated. Patients were administered Berlin questionnaire and
Epworth sleepiness score (ESS) before discharge. The scales were compared between the two groups and
the patients' SYNTAX score.
Results: The rate of high risk patients according to Berlin questionnaire and ESS was found statistically
significant in NSTEMI patients compared to the STEMI group (p <0.001, p = 0.023). The total amount of
points determined in Berlin questionnaire and ESS was statistically significant in NSTEMI patients
compared to the STEMI group (p <0.001). In Pearson correlation analysis, a significant positive correlation
was found between the SYNTAX score and the total score determined in the Berlin questionnaire, and
between the SYNTAX score and ESS (r = 0.865, p <0.001 and r = 0.761, p <0.001).
Conclusion: In this study, the relationship between OSAS and ACS was evaluated. Berlin
questionnaire and ESS results were higher than the literature, and a positive correlation was found
between the SYNTAX score and OSAS risk.