TY - JOUR
AR - JCMCR-2020-1-101
TI - An Almost Fatal Case of the Hypereosinophilic Syndrome: A Dilemma Between Vasculitis or Clonal Disorder
AU - Aharon, Kessel
AU - Alona, Paz
AU - Anna, Solopov
AU - Boaz, Weller
AU - Doron, Rimar
AU - Idit, Dobrecky-Mery
AU - Ilana, Levy
AU - Liliana, Schliamser
AU - Milian, Croitoru
AU - Nizar, Jiries
AU - Shira, Ginsberg
AU - Tamar, Tadmor
JO - Journal of Clinical and Medical Case Reports
PY - 2020
DA - Thu 26, Dec 2019
SN - 2733-2268
DO - http://dx.doi.org/10.31487/j.JCMCR.2019.01.01
UR - https://www.sciencerepository.org/an-almost-fatal-case-of-the-hypereosinophilic-syndrome_JCMCR-2019-1-101 
KW - 
AB - Hypereosinophilic syndrome (HES) is a rare and potentially life-threatening disorder. While many
conditions can cause eosinophilia, it can also be provoked by rarer diseases such as vasculitis or
myeloproliferative disorders. Here we present an almost fatal presentation of HES characterized with both
vasculitis and clonal features. Treatment with combined chemo-immunotherapy allowed reversal of most
of the complications. There is still much uncertainty in the diagnosis and management of HES, and research
should be done to improve knowledge on pathophysiology and cytogenetics of this disease in order to
improve treatment and prevent life-threatening complications.