TY - JOUR AR - DOBCR-2019-4-102 TI - The Use of Platelet-Rich Plasma Alone in The Treatment of Periodontal Endosseous Defects: A Report of Two Clinical Cases AU - Eudoxie, Pepelassi AU - Harry Charalabos, Stamatakis AU - Ioannis, Vrotsos AU - Nikolaos, Markou AU - Sotirios, Kotsovilis JO - Dental Oral Biology and Craniofacial Research PY - 2019 DA - Mon 30, Sep 2019 SN - 2613-4950 DO - http://dx.doi.org/10.31487/j.DOBCR.2019.04.02 UR - https://www.sciencerepository.org/the-use-of-platelet-rich-plasma-alone-in-the-treatment-of-periodontal-endosseous-defects-a-report-of-two-clinical-cases_DOBCR-2019-4-102 KW - Periodontitis, periodontal treatment, monotherapy, periodontal endosseous defects, platelet-rich plasma AB - Background: On the basis of animal histologic data and randomized controlled trials, the authors provide reports of two cases, in which platelet-rich plasma (PRP) alone was used to treat periodontal endosseous defects in patients exhibiting generalized severe chronic periodontitis. Case Descriptions: Clinicians treated endosseous defects with a probing pocket depth of 6 and 8 millimeters (case 1), and 4 mm (case 2) by using PRP alone. At six months, complete periodontal pocket resolution, and significant clinical attachment gain and radiographic defect fill, compared with pre-surgical values, occurred in all defects. Clinical Implications: PRP alone may be clinically and radiographically efficacious in the treatment of periodontal endosseous defects.