TY - JOUR
AR - COR-2021-12-101
TI - Factors Influencing the Prognosis of Acute Myeloid Leukemia
AU - Yi-Qian, ZHU
AU - Fei , Wang
AU - Xue , Wu
AU - Bao-An, Chen
JO - Clinical Oncology and Research
PY - 2021
DA - Wed 29, Dec 2021
SN - 2613-4942
DO - http://dx.doi.org/10.31487/j.COR.2021.12.01
UR - https://www.sciencerepository.org/factors-influencing-the_COR-2021-12-101 
KW - Acute myeloid leukemia, survival rate, influencing factors
AB - Objective: To investigate the prognostic factors of adult acute myeloid leukemia (AML). 
Methods: A total of 51 patients with AML initially treated in Zhongda Hospital affiliated to Southeast University in the past 7 years were selected to investigate the gender, age (60-year-old) and WBC count (>=30*109/L), whether there is a history of MDS and other factors related to survival rate.
Results: The results showed that age and the history of MDS prodrome were independent prognostic factors affecting OS. The OS rates of CD19 negative, CD11b positive and CD64 negative patients were significantly lower than those without the above factors at the onset of the disease, and the differences were statistically significant (all P<0.05).
Conclusion: The prognosis of AML patients is affected by multiple factors, so prognosis should be stratified according to risk factors, and appropriate chemotherapy regimens should be selected for patients of different age groups.