TY - JOUR AR - COR-2020-3-112 TI - Metastatic Anal Lesion of Primary Lobular Breast Carcinoma- An Insidious, Rare and Subclinical Progression: Case Report and Review of the Literature AU - Aisoni F, AU - Bonazza S, AU - Carcoforo P, AU - D’Urbano F, AU - Fabbri, Nicolò AU - Pedriali M, AU - Soliani G, JO - Clinical Oncology and Research PY - 2020 DA - Mon 30, Mar 2020 SN - 2613-4942 DO - http://dx.doi.org/10.31487/j.COR.2020.03.12 UR - https://www.sciencerepository.org/metastatic-anal-lesion-of-primary_COR-2020-3-112 KW - Breast cancer, metastasis, anal canal, case report AB - Gastrointestinal metastasis from primary breast carcinoma is very uncommon, with less than 1% of breast carcinomas metastasize to the gastrointestinal tract but anorectal involvement is even rarer. These metastatic lesions can lead to diagnostic challenge for clinicians as they can mimic primary colo-rectal cancer due to the lack of diagnostic signs. The increase of patient survival could lead to an unusual late resumption of metastatic disease, often for a long-time occult. Nowadays, an almost completely absent literature is unable to suggest diagnostic pathways capable of predicting this type of disease evolution. We present the case of a 76-year old woman who underwent treatment for an infiltrative lobular carcinoma of the breast who developed metastasis of the anal canal 11- years later. A literature review was performed.