TY - JOUR
AR - COR-2019-6-104
TI - Management and Outcomes of Spontaneous Rupture of Hepatocellular Carcinoma: Current Practice
AU - Ahmad, Mirza
AU - Arslan, Pannu
AU - Eloise, Lawrence
AU - Ghulam Murtaza, Dar
AU - Khurram, Khan
AU - Salman, Jabbar
AU - Shahzad, Ahmed
JO - Clinical Oncology and Research
PY - 2019
DA - Thu 28, Nov 2019
SN - 2613-4942
DO - http://dx.doi.org/10.31487/j.COR.2019.06.04
UR - https://www.sciencerepository.org/management-and-outcomes-of-spontaneous-rupture-of-hepatocellular_COR-2019-6-104 
KW - Ruptured hepatocellular carcinoma, trans-arterial embolization, resection, computed tomographic scan
AB - Objectives: To review the current management options for ruptured hepatocellular carcinoma (HCC) at
acute presentation and assess the impact of each treatment modality on short- and long-term patient related
outcome.
Study design: A PubMed search was undertaken for review articles from 1950 to 2019 using key phrases
“Ruptured hepatocellular carcinoma”, “trans-arterial embolization”, “resection”, “computed tomographic
scan” and “conservative management”. Further manual search was performed to identify key articles from
the reference list.
Methodology: All papers with previous described management for ruptured HCC were reviewed. The
morbidity, mortality and comparison of various management options were reviewed. Current practice
guidelines were visited to identify common practice protocols.
Conclusion: Ruptured HCC is associated with significant morbidity and mortality. Multiple management
options can be applied guiding by patient’s overall condition. Conservative management is associated with
overall poor outcome. Staged liver resection is associated with better outcome with improved morbidity and
mortality.