TY - JOUR
AR - CDM-2020-2-101
TI - MDCT Evaluation of Hepatic Manifestations in Malignant Hematological Disorders
AU - Adel , El-Badrawy
AU - Ahmed , Tawfik
AU - Gehad , Saleh
AU - Mai , Abdel-Naby
AU - Hayam , Ghazy
AU - Ziad , Emarah
AU - Ahmed , Ramez
AU - Mohamed , A. Elfatah
AU - Ahmed , Eltantawy
AU - Mona ,  M. Taalab
AU - Noha , Eisa
AU - Shaimaa , El-Ashwah
AU - Yasmine , Essam
AU - Basma , Atef
AU - Shahira Ali , El-Etreby
AU - Monir , H. Bahgat
AU - Ahmed , Deiab
AU - Hatem , Elalfy
AU - Tarek , Besheer
AU - Ahmed , El-Mesery
AU - Mohamed , Mahmoud Sarhan
AU - Suzy , Abd Elmabood
AU - Ahmed , Megahed
AU - Mohamed , Farouk Akl
AU - Khaled , Abouelkhair
AU - Hanan , Wahba
AU - Amal , Halim
AU - Nirmeen , Megahed
AU - Eman , Omar Khashaba
JO - Cardiovascular Disorder and Medicine
PY - 2020
DA - Thu 19, Nov 2020
SN - 
DO - http://dx.doi.org/10.31487/j.CDM.2020.02.01
UR - https://www.sciencerepository.org/mdct-evaluation-of-hepatic-manifestations-in-malignant-hematological-disorders_CDM-2020-2-101 
KW - Liver, hematological malignancies, computed tomography
AB - Objective: The aim of this work was to evaluate Multidetector Computed Tomography (MDCT) findings
of hepatic manifestation in common malignant hematological disorders.
Materials and Methods: This retrospective study included 300 patients with different types of malignant
hematological disorders. They were 119 female and 181 male (mean age, 45.4 year; range, 5-70 years). The
most common hematological disorder was Non-Hodgkin lymphoma (NHL) detected in 192/300 (64%)
patients and then Hodgkin disease (HD) detected in 40/300 (13.3%) patients. All 300 patients had
ultrasonography. Clinical evaluation and laboratory assessment were done for all patients. Whole body and
triphasic abdominal CT scanning was performed on 64 MDCT systems.
Results: MDCT scanning revealed hepatic affection in 82/192 of NHL. All these 82 cases revealed
hepatomegaly and focal lesion detected in 36 cases. As regard Hodgkin disease (HD), hepatomegaly
detected in 22/40 cases and focal lesion detected in 8/40 cases. Hepatomegaly detected in 8/14 cases of
acute myeloid leukemia (AML) and focal lesion detected in 4/14 cases. In cases of chronic lymphocytic
leukemia (CLL), hepatomegaly detected in 6/22 cases with no detection of focal lesion.
Conclusion: Hepatic involvement is often observed in several malignant hematological disorders, resulting
in abnormalities in liver imaging studies. Malignant hematological disorders must be considered in
hepatomegaly and hepatic focal lesions either single or multiple. MDCT is the diagnostic modality of choice
for diagnosis and follow up of liver affection in different malignant hematological disorders.