article = {JSO-2020-2-108}
title = {Dedifferentiated Chondrosarcoma with Epithelial Differentiation: A Case Report and Review of the Literature}
journal = {Journal of Surgical Oncology}
year = {2020}
issn = {2674-3000}
doi = {http://dx.doi.org/10.31487/j.JSO.2020.02.08}
url = {https://www.sciencerepository.org/dedifferentiated-chondrosarcoma-with-epithelial-differentiation_JSO-2020-2-108 
author = {Humaid Al Farii,Marc-Antoine  Ricard,Motaz  AlAqeel,Robert  Turcotte,Sungmi  Jung ,}
keywords = {Dedifferentiated chondrosarcoma, epithelial dedifferentiation}
abstract ={Case: We describe a case of 72-year-old male with dedifferentiated chondrosarcoma with osteosarcomatous
and epithelioid (squamous) dedifferentiation. As first described in the literature by Dahlin and Beabout, a
well-differentiated benign chondral lesion abruptly juxtaposed to a high-grade non-cartilaginous component
is the classical definition of a chondrosarcoma [1]. The non-cartilaginous component is typically an
osteosarcoma, fibrosarcoma or malignant fibrous histiocytoma with rare instances of leiomyosarcoma, giant
cell tumor and rhabdomyosarcoma [2].
Conclusion: We report our rare instance of squamous dedifferentiation of a dedifferentiated
chondrosarcoma along with other five cases that have been reported so far in the literature}