article = {JICOA-2018-1-106} title = {Research to Observe the Hemodynamic Changes and Cardiac Function in Active Abdominal Compression-decompression Cardiopulmonary Resuscitation} journal = {Journal of Integrative Cardiology Open Access} year = {2018} issn = {2674-2489} doi = {http://dx.doi.org/10.31487/j.JICOA.2018.01.006} url = {https://www.sciencerepository.org/research-to-observe-the-hemodynamic-changes-and-cardiac-function-in-active-abdominal-compression-decompression-cardiopulmonary-resuscitation_JICOA-1-106 author = {Cunqing Zhang,Hongwei Wang,Jing Li,Lixiang Wang,Longxian Zhao,Sisen Zhang,Ting Liu,Yingxin Cen,} keywords = {Transthoracic echocardiography, cardiac arrest, cardiopulmonary resuscitation, haemodynamics, cardiac function} abstract ={Objective: Compare the hemodynamic changes and cardiac function between active abdominal compressiondecompression cardiopulmonary resuscitation and standard cardiopulmonary resuscitation. Methods: A prospective controlled trial was conducted. The patients staying in EICU or ICU were the study subjects which were divided into active abdominal compression-decompression cardiopulmonary resuscitation (AACD-CPR) group and standard cardiopulmonary resuscitation (STD-CPR) group randomly. Central venous pressure (CVP), diastolic blood pressure (DBP) and coronary perfusion pressure (CPP) were recorded continuously. Transesophageal echocardiography (TEE) was used to observe the cardiac valves and assess left ventricular end diastolic volume (LVEDV), left ventricular end systolic volume (LVESV), left ventricular ejection fraction (LVEF) during CPR. Results: During CPR, LVEDV of two groups both decreased compared with pre-cardiac arrest, which was not statistically significant(P>0.05). LVEDV in AACD-CPR group was larger than STD-CPR group during CPR. But there was not statistically significant (P>0.05). During CPR, LVESV of two groups both increased compared with pre-cardiac arrest, which was statistically significant(P<0.01). LVESV in AACD-CPR group was larger than STDCPR group(P<0.05). But there was not statistically significant(P>0.05). Both AACD-CPR group and STD-CPR group showed significantly decreased LVEF compared with pre-cardic arrest, of which the difference was statistically significant(P<0.01). LVEF in STD-CPR group was higher than AACD-CPR group and there was a tatistically significant difference between them(P<0.05). When compressing chest , mitral valve and tricuspid valve were open and aortic valve and pulmonary valve were closed during the 8 patients of the STD-CPR group. Conclusion: During chest compression, heart pump took effect in a part of patients. However, during abdominal compression, heart was just a channel that blood flowed. The cardiac function in STD-CPR was superior to AACDCPR. However, both of them can produce effective haemodynamics. So, we suggested that AACD-CPR could be used in the patients with the contraindication of STD-CPR.}