article = {JCMCR-2020-1-101}
title = {An Almost Fatal Case of the Hypereosinophilic Syndrome: A Dilemma Between Vasculitis or Clonal Disorder}
journal = {Journal of Clinical and Medical Case Reports}
year = {2020}
issn = {2733-2268}
doi = {http://dx.doi.org/10.31487/j.JCMCR.2019.01.01}
url = {https://www.sciencerepository.org/an-almost-fatal-case-of-the-hypereosinophilic-syndrome_JCMCR-2019-1-101 
author = {Aharon Kessel,Alona Paz,Anna Solopov,Boaz Weller,Doron Rimar,Idit Dobrecky-Mery,Ilana Levy,Liliana Schliamser,Milian Croitoru,Nizar Jiries,Shira Ginsberg,Tamar Tadmor,}
keywords = {}
abstract ={Hypereosinophilic syndrome (HES) is a rare and potentially life-threatening disorder. While many
conditions can cause eosinophilia, it can also be provoked by rarer diseases such as vasculitis or
myeloproliferative disorders. Here we present an almost fatal presentation of HES characterized with both
vasculitis and clonal features. Treatment with combined chemo-immunotherapy allowed reversal of most
of the complications. There is still much uncertainty in the diagnosis and management of HES, and research
should be done to improve knowledge on pathophysiology and cytogenetics of this disease in order to
improve treatment and prevent life-threatening complications.
}