Table 2: Multivariate analyses of prognostic factors for
overall survival in patients with gastrointestinal mucosal melanomas.
|
Variable |
P-value |
Hazard ratio |
95.0% CI for hazard ratio |
||
|
Lower |
Upper |
||||
|
Sex |
Male |
- |
- |
- |
- |
|
|
Female |
0.615 |
0.734 |
0.220 |
2.446 |
|
Age (years) |
≤60 |
- |
- |
- |
- |
|
|
>60 |
0.617 |
0.777 |
0.289 |
2.088 |
|
Primary or metastatic |
Primary |
- |
- |
- |
- |
|
|
Metastatic |
0.038 |
13.062 |
1.160 |
147.127 |
|
Tumor location |
Upper gastrointestinal tract |
- |
- |
- |
- |
|
|
Lower gastrointestinal tract |
0.040 |
14.993 |
1.136 |
197.823 |
|
Number of lesions |
Single |
- |
- |
- |
- |
|
|
Multiple |
0.809 |
0.806 |
0.140 |
4.632 |
|
Initial symptoms |
Bleeding (haematochezia or haematemesis) |
- |
- |
- |
- |
|
|
Non-bleeding |
0.160 |
2.628 |
0.683 |
10.110 |
|
Distant metastasis |
Yes |
- |
- |
- |
- |
|
|
No |
0.660 |
0.729 |
0.178 |
2.988 |
|
Lymph node metastasis |
Yes |
- |
- |
- |
- |
|
|
No |
0.132 |
3.394 |
0.692 |
16.635 |
|
Melan A (immunohistochemical analysis) |
(+) |
- |
- |
- |
- |
|
|
(-) |
0.152 |
5.777 |
0.524 |
63.747 |
|
Treatments |
No (had not received any treatment or had received only
palliative care) |
- |
- |
- |
- |
|
|
Only surgery |
0.061 |
5.770 |
0.922 |
36.103 |
|
|
Only chemotherapy |
0.237 |
6.540 |
0.291 |
147.070 |
|
|
Both surgery and chemotherapy |
0.281 |
2.686 |
0.446 |
16.183 |