Table 2: Multivariate analyses of prognostic factors for overall survival in patients with gastrointestinal mucosal melanomas.

Variable

P-value

Hazard ratio

95.0% CI for hazard ratio

Lower

Upper

Sex

Male

-

-

-

-

 

Female

0.615

0.734

0.220

2.446

Age (years)

≤60

-

-

-

-

 

>60

0.617

0.777

0.289

2.088

Primary or metastatic

Primary

-

-

-

-

 

Metastatic

0.038

13.062

1.160

147.127

Tumor location

Upper gastrointestinal tract

-

-

-

-

 

Lower gastrointestinal tract

0.040

14.993

1.136

197.823

Number of lesions

Single

-

-

-

-

 

Multiple

0.809

0.806

0.140

4.632

Initial symptoms

Bleeding (haematochezia or haematemesis)

-

-

-

-

 

Non-bleeding

0.160

2.628

0.683

10.110

Distant metastasis

Yes

-

-

-

-

 

No

0.660

0.729

0.178

2.988

Lymph node metastasis

Yes

-

-

-

-

 

No

0.132

3.394

0.692

16.635

Melan A (immunohistochemical analysis)

(+)

-

-

-

-

 

(-)

0.152

5.777

0.524

63.747

Treatments

No (had not received any treatment or had received only palliative care)

-

-

-

-

 

Only surgery

0.061

5.770

0.922

36.103

 

Only chemotherapy

0.237

6.540

0.291

147.070

 

Both surgery and chemotherapy

0.281

2.686

0.446

16.183