- Severe pain or local anaesthesia
- Rapid progression of erythema, edema (tenderness), pain
- Blistering- hemorrhagic bullae
- Foul odor
- Purulent collection or brownish-tan “dishwater” drainage (sinuses)
- Skin sloughing/necrosis
- Crepitus (12 patients)
- SIRS - 9 patients
- Sepsis and/or MODS - 9 patients
* LRINEC score ≥6 - 6 patients
>8 - 12 patients
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- Pain (disproportional), fever
- Erythema, skin bronzing- discoloration
- Local warmth (hyperthermia)
- Tense edema beyond area of erythema
- Induration- epidermolysis
- Numbness
* LRINEC score 5 - 3 patients
6 - 3 patients
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