Table 4: Median and 1- and 5-year survival probabilities for 1,004 patients diagnosed with dedifferentiated liposarcoma by age, sex, race, stage, primary site, treatment group, Charlson-Deyo score, and surgical margins.
Variable |
Probability of 1-Year Survival (%) |
Probability of 5-Year Survival (%) |
Median Survival (months) |
Overall Survival |
86.8 |
55.5 |
73.3+3.9 |
Age Group (years) |
|
|
|
0-20 |
100 |
* |
* |
21-40 |
94.4 |
77.3 |
* |
41-60 |
89.0 |
57.9 |
* |
61-80 |
83.6 |
43.9 |
* |
>80 |
83.7 |
23.1 |
* |
Sex |
|
|
|
Male |
85.7 |
55.3 |
73.3+11.6 |
Female |
88.8 |
56.1 |
75.6.5+11.2 |
Race |
|
|
|
White |
87.1 |
55.9 |
73.3+5.2 |
African American |
84.6 |
55.7 |
63.5a |
Other |
84.2 |
50.6 |
* |
Metastasis Status |
|
|
|
Metastasis |
50.8 |
17.7 |
16.3+6.6 |
No Metastasis |
88.5 |
57.4 |
73.4+3.6 |
Primary Site |
|
|
|
Head or Neck |
* |
* |
* |
(Retro)Peritoneum/Abdomen |
84.2 |
46.8 |
* |
Thorax/Trunk |
87.2 |
58.9 |
* |
Extremities |
93.8 |
69.0 |
* |
Pelvis |
87.8 |
72.4 |
* |
Tumor Grade |
|
|
|
High |
85.9 |
54.0 |
72.2+5.0 |
Low |
95.2 |
71.7 |
* |
Therapy Group |
|
|
|
No Chemotherapy or Radiation |
83.9 |
46.5 |
63.5a |
Neoadjuvant Chemotherapy or Radiation |
88.4 |
56.9 |
75.6+13.1 |
Adjuvant Chemotherapy or Radiation |
88.5 |
48.1 |
73.3+3.8 |
Charlson-Deyo Score |
|
|
|
0 |
88.1 |
57.1 |
73.4+3.5 |
1 |
80.8 |
48.2 |
51.7+12.0 |
2 |
83.4 |
52.9 |
* |
3+ |
92.9 |
63.7 |
* |
Surgical Margins Status |
|
|
|
No Residual Tumor |
90.2 |
61.0 |
73.4a |
Microscopic Residual Tumor |
87.5 |
54.9 |
73.3+14.3 |
Macroscopic Residual Tumor |
69.8 |
44.0 |
31.3+7.5 |
Residual Tumor, NOS |
79.6 |
44.9 |
55.2+8.6 |
Indeterminate |
84.6 |
42.5 |
50.0+3.9 |
*: Median or percent survival data not available.
a: Error data not available due to sample size limitations.