Table 1: Baseline Demographics.
|
|
Early (n=36) |
Late (n=10) |
P-value |
|
Age – years, median (SD) |
70.5 (9.6) |
65.5 (9.7) |
0.9445 |
|
Male – n (%) |
20 (55.5) |
5 (50) |
0.7322 |
|
Race – n (%) |
|
|
|
|
White |
24 (66.6) |
3 (30) |
0.0672 |
|
Black |
7 (19.4) |
7 (70) |
0.0045 |
|
Other |
5 (14) |
0 |
0.3359 |
|
Weight – kilograms, median (SD) |
78.2 (25.5) |
63.6 (18.8) |
0.3754 |
|
BMI – kg/m2, median (SD) |
26.5 (8.3) |
25 (6.5) |
0.2352 |
|
Past medical history – n (%) |
|
|
|
|
Chronic Kidney Disease |
8 (22.2) |
2 (20) |
0.9999 |
|
Congestive Heart Failure |
8 (22.2) |
1 (10) |
0.6590 |
|
Diabetes Mellitus |
13 (36.1) |
2 (20) |
0.4599 |
|
Hypertension |
21 (58.3) |
5 (50) |
0.7264 |
|
Immunosuppression |
6 (16.7) |
0 (0) |
0.3145 |
|
Liver Disease |
11 (30.5) |
1 (10) |
0.2524 |
|
Malignancy |
6 (16.7) |
6 (60) |
0.0117 |
|
Intensive Care Unit – n (%) Medical Surgical/Trauma Surgical/Cardiothoracic Cardiac Neurosciences/Neurosurgery |
14 (39) 16 (44.4) 0 (0) 3 (8.3) 3 (8.3) |
10 (100) 0 (0) 0 (0) 0 (0) 0 (0) |
0.0006 0.0202 0.9999 0.5850 0.5850 |
|
APACHE II score – median (IQR) |
26 (24, 32.75) |
32 (27, 43) |
0.0952 |
|
SOFA score – median (IQR) |
12.5 (8.25, 13.75) |
14 (12, 16) |
0.0192 |
Note: SD: Standard Deviation, APACHE II: Acute Physiology and Chronic Health Evaluation II, SOFA: Sequential Organ Failure Assessment, IQR: Interquartile Range.