Authors

Country

n

Sex

Age at LT †

 (years)

Previous treatment

Pathological findings

Immunosuppressive therapy

Follow-up after LT †

Strong et al. [1] (2002)

Australia

4

2♀

2♂

35 ± 12

n=1 cholecystectomy and choledochojejunostomy at 13-year-old ¶

n=1 cholecystectomy Roux-en-Y hepatico-jejunostomy.

n=1 hemihepatectomy and choledochectomy

n=1 multiple ERCP ‡

Dilated ducts packed and hepatolithiasis

n.r. §

n=1 uneventful and alive 14 years later.

n=1 p.o.* period necessitated biliary reconstruction for partial necrosis of the bile duct. Uneventful and alive 7 years later.

n=1 uneventful and alive 5 years later.

n=1 uneventful and alive 4.5 years later.

Hirohashi et al. [2] (2004)

Japan

1

 ♀

43

Cholecystectomy at 15-year-old ¶

Choledocolitotomy at 29-year-old ¶

Preoperative percutaneous transhepatic biliary drainage for biliary bronchial fistula treatment.

Hepatolithiasis

Azathioprine + Tacrolimus + Mycophenolate mofetil

P.o.* bile leak treated with conservative treatment.

Uneventful and alive 7 months later.

Pan et al. [3] (2005)

China

4

1♀

3♂

n.r. §

n.r. §

Biliary liver cirrhosis and hepatolithiasis

n.r. §

n=3 p.o.* bleeding from the digestive tract.

n=1 leakage intestinal anastomosis.

Zang series reported by Feng et al. [4] (2016)

China

6

n.r. §

n.r. §

Operation history n=4

Liver cirrhosis without cholangiocarcinoma

n.r. §

Survival rate 96 months.

Tang et al.

[5] (2008)

China

1

♂

45

n.r. §

Liver cirrhosis and hepatolithiasis

Tacrolimus + Mycophenolate mofetil + Corticosteroids

Uneventful and alive 40 months later.

Chen et al. [6] (2010)

China

15

9♀

6♂

38.5 ±7.9

Upper abdominal operation on the biliary tract 1-5 times before LT †.

Two cases of cholangiocarcinoma

Ciclosporine/Tacrolimus + Mycophenolate mofetil + Corticosteroids

Mean 55 months (range 12-79).

No deaths or hospital readmissions after LT † are reported.

Ray et al. [7] (2016)

India

3

n.r. §

n.r. §

n.r. §

Secondary biliary cirrhosis

n.r. §

n.r. §

Present cases (2020)

Spain

2

 2 ♂

 38 ±4.2

n=2 cholecystectomy at 21 and 38-year-old and multiple ERCP ‡ after that.

Intraductal papillomatosis with dysplasia and cirrhosis

Tacrolimus + Mycophenolate mofetil + Corticosteroids

n=1 uneventful and alive 7 years later.

n=1 cholangitis and alive 6 years later.