Table 3: Some diagnoses.




 

Total cases monitored 2,541 children (Prevalence)

Monitored cases with ADD/ADHD

Percentage of monitored cases with ADD/ADHD

New cases (Incidence) since 1-1-2016

New cases with ADD/ADHD since 1-1-2016

Percentage of new cases with ADD/ADHD since 1-1-2016

ADD/ADHD alone*

530

 

 

187

 

 

Associated ADD/ADHD**

513

 

 

52

 

 

Epilepsy

429

134

31%

36

5

13,9%

Tics

159

107

67,3%

37

20

54%

Perinatal encephalopathy

131

35

26,7%

3

1

3%

Adopted children

87

54

62%

27

11

40,7%

Chromosomopathy-encephalopathy

64

31***

48,4%

1

0

 

Rolandic epilepsy

36

10

27,8%

9

3

33,3%

Eastern European adopted children

35

26

74,3%

9

6

 

Absence epilepsy

35

19

54,3%

0

0

 

Neurofibromatosis 1

35

18

51,4%

0

 

 

Genopathy-encephalopathy

18

4****

22,2%

1*****

1*****

100%

Tuberous sclerosis

14

4

28,6%

0

 

 

Hemispheric tumour

10

3

30%

1

0

 

Down’s syndrome

9

1

11,1%

1

0

 

Fragile-X syndrome

8

7

87,5%

0

 

 

Duchenne muscular dystrophy

8

4

50%

0

 

 

Dravet syndrome with SCN1A mutation

5

2

40%

0

 

 

Myelomeningocele

5

2

40%

0

 

 

Sturge-Weber syndrome

2

2

100%

0

 

 

Prader Willi syndrome

2

2

100%

0

0

 

Female fragile-X premutation carrier

1

1

100%

0

0

 

Total: 2,541 children monitored from 1-1-2016 to 19-6-2017, born after 31-12-2009 (more than 7½ years old). The table shows the different diagnoses (column 1), the total number of monitored children with each diagnosis (column 2), the monitored cases diagnosed with ADD/ADHD for each diagnosis (column 3), the percentage of monitored children in each diagnosis who have ADD/ADHD (column 4), the new cases of each diagnosis (column 5), the new cases of ADD/ADHD in each diagnosis (column 6), and the percentage of new children in each diagnosis who have ADD/ADHD (column 7).

*ADD/ADHD alone. It may be accompanied by learning disorders, headaches, isolated arachnoid cysts or Chiari malformation type I. Adopted children are included, except Eastern European adopted children, if they do not present any other pathologies.

**Associated ADD/ADHD. It may be associated with: ASD, Asperger, intellectual disability, any type of epilepsy, NF1, tuberous sclerosis, Sturge-Weber syndrome, Tourette or tics, cerebral palsy, genopathy-encephalopathy, chromosomopathy-encephalopathy, Eastern European adopted children (considered probable foetal alcohol effect), dystrophinopathy, acquired encephalopathies (shaken baby syndrome, post-traumatic brain injury, acquired CNS infection), myelomeningocele, brain tumor.

***Chromosomopathies with ADD/ADHD, 30 cases: four cases of 16p11.2 deletion, four cases of 22q11.4 deletion, two cases of 1q21.1 deletion (one also with Fragile-X), two cases of 17q12 duplication and two cases of XYY syndrome. 16 cases of different alterations: 2q24 deletion, 3p26.3 3p26.1 duplication and 3p26.3 deletion, 5q12 deletion, 7q36.3 deletion and 20q13.32 duplication, 8q11 deletion (Silver-Russel-like syndrome), 10p15.3 deletion, 12q15 q21.1 deletion, 15q11 deletion, 15q13.3 deletion,15q26 deletion and 7p22 duplication, 18q deletion, 21q22.3 deletion, 22q11 .1 deletion and Xp22.31 duplication, trisomy 8p12, mosaic tetrasomy 9p, Xq28 duplication and triple X syndrome.

****Genopathies with ADD/ADHD, apart from fragile-X: Kabuki, Silver Russel, Williams Beuren and *****Noonan.