Table 2: Factors improving behavior after surgical ablation or HI perinatal injury.

Factor

Model

Example References

Outcome

Behavioral therapies
  1. Complex housing at weaning

SA

[70]

é vision
  1. Complex housing in adulthood

SA

[73]

é vision
  1. Complex housing at weaning

HI

[72]

écognition, émotor
  1. Tactile stimulation

SA

[74]

émotor
  1. Prenatal tactile stimulation

SA

[59]

écognition, émotor
  1. Diet (e.g., sulforaphane pre/post)

HI

[52]

écognition, émotor
  1. Diet (e.g, vitamin/minerals)

SA

[75]

émotor
  1. Mild hypothermia

HI

[76]

écognition, émotor

Pharmacotherapies
  1. FGF-2

SA

[77]

é vision
 

SA

[66]

écognition, émotor
  1. Gestational FGF-2

SA

[77]

émotor
  1. FGF-2 (HI)

HI

[53]

écognition, émotor
  1. Nicotine

HI

[78]

écognition, émotor
  1. Gestational diazepam

SA

[79]

émotor
  1. Docosahexaemoic acid (DHA)

HI

[80]

écognition, émotor
  1. Creatine

HI

[81]

émotor
  1. Choline

SA

[82]

écognition
  1. BDNF

HI

[83]

écognition

écognition, émotor indicates improved performance on cognitive or motor tasks.

SA: surgical ablation; HI: hypoxic/ischemic. Treatments are given postinjury unless noted otherwise.