Table 1: Clinicopathological characteristics of patients with rectal adenocarcinoma and their correlations with MTSS1 expression.

Characteristics

Number of cases (%)

MTSS1 expression (%)

P value

Low or no expression

High expression

 

Age (years, median 59 years)

 

 

 

P=0.528

median

88(48.9)

61(50.8)

27(45)

 

≥median

92(51.1)

59(49.2)

33(55)

 

Gender

 

 

 

P=0.749

Male

104(57.8)

68(56.7)

36(43.3)

 

Female

76(42.2)

52(60.0)

24(40.0)

 

Pathologic differentiation

 

 

 

P=0.255

Well

10(5.6)

7(5.8)

3(5.0)

 

Moderately

148(82.2)

95(79.2)

53(88.3)

 

Poorly

22(12.2)

18(15)

4(6.7)

 

T stage

 

 

 

P<0.001

T 1

5(2.7)

0(0)

5(8.4)

 

T 2

46 (25.6)

19(15.8)

27(45.0)

 

T 3

46(25.6)

35(29.2)

11(18.3)

 

T 4

83(46.1)

66(55.0)

17(28.3)

 

N stage

 

 

 

P=0.002

N0

91(50.6)

50(41.7)

41(68.3)

 

N1

54(330)

48(40.0)

6(10.0)

 

N2

35(19.4)

22(18.3)

13(21.7)

 

M stage

 

 

 

P=0.275

M0

171(95)

112 (93.3)

59(98.3)

 

M1

9(5)

8(6.7)

1(1.7)

 

Dukes stage

 

 

 

P<0.001

A

37(15.0)

8(6.7)

29(48.30)

 

B

50(16.4)

38(31.7)

12(20.0)

 

C

84(68.6)

66(55.0)

18(30.0)

 

D

9(76.4)

8(6.7)

1(1.7)

 

UICC stage

 

 

 

P<0.001

I

37 (20.6)

8(6.7)

29(48.3)

 

II

50(27.8)

38(31.7)

12(20.0)

 

III

84(46.7)

66(59.2)

18(30.0)

 

IV

9(5)

8(6.7)

1(1.7)

 

Surgical method

 

 

 

P=0.134

Harfmann's

8(4.4)

7(5.8)

1(1.7)

 

Miles'

41(22.8)

31(25.8)

10(16.7)

 

Dixon's

131(72.8)

82(68.3)

49(81.7)

 

Recurrence

 

 

 

P<0.001

No

141(78.3)

82(68.3)

59(98.3)

 

Yes

39(21.7)

38(37.1)

1(1.7)

 

Vital status (at follow-up)

 

 

 

P<0.001

Alive

114(63.3)

59(49.2)

55(91.7)

 

Dead

66(36.7)

61(50.8)

5(8.3)