Table 1: Differential diagnosis of CNS papillary tumors.

Tumor Type	Location	Positive Antibodies
Meningioma, papillary type GIII	Dura based extra axial	EMA cytoplasmic, PR nuclear
Ependymoma, papillary type GII, GIII	Wall of the ventricles and spine	GFAP, EMA dot
Myxopapillary Ependymoma GI	Spine, filum terminal	GFAP, EMA dot
Papillary glioneuronal tumor GI	Temporal	GFAP, OLIG2 in perivascular astrocytes Synaptophysin, Neu-N in neurocytes
Choroid plexus neoplasm GI, GII, GIII	Lateral ventricles	CK, VIMENTIN, CK7
Papillary tumor of Pineal Region	Pineal region	Cam5.2, CK18 S100, CD56
Pituitary adenoma	Sellar, Suprasellar	Synaptophysin Pit. Hormones Transcription Factor
Craniopharyngioma, papillary type GI	Suprasellar or 3^rdventricle	EMA, P63, CK7, Cludin B-Catenin membranous. BRAF- V600E mutation
Endolymphatic sac tumor	Posterior medial petrous ridge of temporal bone (site of endolymphatic sac)	CK, CK7 PAS positive colloid like material.
Metastatic Papillary Carcinoma	Anywhere	CK7, CA125, WT-1 Ovary CK7, TTF1, Napsin-A lung CK7, TTF-1, Thyroglobulin Thyroid CK7, CD117, AMACAR Papillary Renal