Table 1: Selected immunohistochemical stains a san aid to the diagnosis of spindle cell tumors of the skin.

Variable

Atypical fibroxanthoma

Dermatofibroma protuberans

Angiosarcoma

Spindle cell SCC

Leiomyosarcoma

Our Case

S100

-

-

-

-

R

-

Desmin

-

-

-

-

+

+

CD34

V

+

V

-

R

-

Factor VIII

-

-

+

-

-

-

CK

-

-

-

+

V

-

EMA

-

-

-

V

-

-

SMA

V

V

V

R

+

+

SCC: squamous cell carcinoma; CK: cytokeratin; EMA: epithelial membrane antigen; SMA: smooth muscle actin; R: rarely positive; V: variable; -: negative; +: positive.