Table 1: Selected immunohistochemical stains a san aid to the diagnosis of spindle cell tumors of the skin.
Variable |
Atypical fibroxanthoma |
Dermatofibroma protuberans |
Angiosarcoma |
Spindle cell SCC |
Leiomyosarcoma |
Our Case |
S100 |
- |
- |
- |
- |
R |
- |
Desmin |
- |
- |
- |
- |
+ |
+ |
CD34 |
V |
+ |
V |
- |
R |
- |
Factor VIII |
- |
- |
+ |
- |
- |
- |
CK |
- |
- |
- |
+ |
V |
- |
EMA |
- |
- |
- |
V |
- |
- |
SMA |
V |
V |
V |
R |
+ |
+ |
SCC: squamous cell carcinoma; CK: cytokeratin; EMA: epithelial membrane antigen; SMA: smooth muscle actin; R: rarely positive; V: variable; -: negative; +: positive.