Table 1: Effect of F. tessmannii on hepatic, kidney and cardiac markers.

Parameters

Groups

Control

Hypertensive

Captopril (20 mg.kg-1)

F. tessmannii (100 mg.kg-1)

F. tessmannii

(200 mg.kg-1)

Concentrations

Protein (mg. mL-1)

62.38±

5.17

90.67±

7.01+++

44.63±

1.66***

42.05±

2.90+***

43.49±

1.60+***

Albumin (mg. mL-1)

35.89±

3.79

63.92±

8.36+++

32.48±

0.54***

28.91±

1.13***

26.97±

0.50***

Creatinine (µmol. L-1)

152.33±

5.99

189.82±

9.47++

132.43±

2.75***

117.29±

4.48+***

113.21±

6.09++***

K+ (mmol. L-1)

5.62±

0.18

5.46±

0.65

5.98±

0.47

5.37±

0.58

5.87±

0.67

Na+ (mmol. L-1)

97.00±

5.76

110.00±

0.67

92.05±

5.25*

118.80±

6.38+

112.70±

2.90

Activities (U.L-1)

Lactate Dehydrogenase

524.6±

104.7

1893.0±

162.1+++

1215.1±

131.6+*

1116.0±

117.6**

1127.0±

232.4*

Aspartate aminotransferase

32.82±

2.74

36.42±

3.55

27.11±

4.29

25.21±

2.15

30.88±

3.19

Alanine aminotransferase

15.71±

5.70

36.34±

6.04+

21.40±

1.76*

23.94±

0.76**

18.73±

1.90*

Ɣ-Glutamyl transpeptidase

1.56±

0.18

2.54±

0.28+

1.14±

0.23**

1.27±

0.26**

1.48±

0.08*

Alkaline phosphatase

19.50±

3.46

36.34±

2.81++

18.38±

4.38**

14.54±

1.23**

17.77±

2.76**

Each value represents mean ± sem, n = 5; F: Fagara; +p < 0.05, ++p < 0.01 and +++p < 0.001: as compared to control group; *p < 0.05, **p < 0.01 and ***p < 0.001: as compared to L - NAME - induced hypertensive rats according to one - way ANOVA followed by Tukey Kramer’s posthoc test.