Table 1: Effect of F. tessmannii on hepatic, kidney and cardiac markers.
|
Parameters |
Groups |
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|
Control |
Hypertensive |
Captopril (20 mg.kg-1) |
F. tessmannii (100 mg.kg-1) |
F. tessmannii (200 mg.kg-1) |
|||||||||||
|
Concentrations |
|||||||||||||||
|
Protein (mg. mL-1) |
62.38± |
5.17 |
90.67± |
7.01+++ |
44.63± |
1.66*** |
42.05± |
2.90+*** |
43.49± |
1.60+*** |
|||||
|
Albumin (mg. mL-1) |
35.89± |
3.79 |
63.92± |
8.36+++ |
32.48± |
0.54*** |
28.91± |
1.13*** |
26.97± |
0.50*** |
|||||
|
Creatinine (µmol. L-1) |
152.33± |
5.99 |
189.82± |
9.47++ |
132.43± |
2.75*** |
117.29± |
4.48+*** |
113.21± |
6.09++*** |
|||||
|
K+ (mmol. L-1) |
5.62± |
0.18 |
5.46± |
0.65 |
5.98± |
0.47 |
5.37± |
0.58 |
5.87± |
0.67 |
|||||
|
Na+ (mmol. L-1) |
97.00± |
5.76 |
110.00± |
0.67 |
92.05± |
5.25* |
118.80± |
6.38+ |
112.70± |
2.90 |
|||||
|
Activities (U.L-1) |
|||||||||||||||
|
Lactate Dehydrogenase |
524.6± |
104.7 |
1893.0± |
162.1+++ |
1215.1± |
131.6+* |
1116.0± |
117.6** |
1127.0± |
232.4* |
|||||
|
Aspartate aminotransferase |
32.82± |
2.74 |
36.42± |
3.55 |
27.11± |
4.29 |
25.21± |
2.15 |
30.88± |
3.19 |
|||||
|
Alanine aminotransferase |
15.71± |
5.70 |
36.34± |
6.04+ |
21.40± |
1.76* |
23.94± |
0.76** |
18.73± |
1.90* |
|||||
|
Ɣ-Glutamyl transpeptidase |
1.56± |
0.18 |
2.54± |
0.28+ |
1.14± |
0.23** |
1.27± |
0.26** |
1.48± |
0.08* |
|||||
|
Alkaline phosphatase |
19.50± |
3.46 |
36.34± |
2.81++ |
18.38± |
4.38** |
14.54± |
1.23** |
17.77± |
2.76** |
|||||
Each value represents mean ± sem, n = 5; F: Fagara; +p < 0.05, ++p < 0.01 and +++p < 0.001: as compared to control group; *p < 0.05, **p < 0.01 and ***p < 0.001: as compared to L - NAME - induced hypertensive rats according to one - way ANOVA followed by Tukey Kramer’s posthoc test.