Table 1: The IRI and HOMA-IR parameters in patients with type 2 DM and CAN (M±m).

Parameters	Patients with type 2 DM (n = 107)
Parameters	Without CAN [group 1 (n = 16)]	Subclinical CAN [group 2 (n = 19)]	Definite CAN [group 3 (n = 72)]	Group 4 [control group (n = 14)]
HbA1c, %	6.58±0.16^*	6.74±0.19^†	7.18±0.11^§**††	5.44±0.17
ІRІ, мcIU/L	16.12±1.15^*	20.06±1.3^†	27.31±1.1^§^§^††**	11.57±0.62
HOMA-IR	4.36±0.47^*	5.73±0.6^†	8.35±0.49^§**††	2.45±0.14

IRI: Immunoreactive Insulin; HOMA-IR: Homeostasis Model Assessment Insulin Resistance; DM: Diabetes Mellitus; CAN: Cardiovascular Autonomic Neuropathy; HbA1c: glycated HbA1c.