Table 4: Effect of esmolol on the torsional and strain variables of LV in intact myocardium.
|
Control |
ESMOLOL |
p |
|
|
LV torsion (o/mm) |
0.12 ± 0.03 |
0.09 ± 0.04 |
p = 0.012 |
|
LV twist (o) |
8.32 ± 2.36 |
6.04 ± 2.65 |
p = 0.008 |
|
LV systolic torsion rate (o/s) |
58.84 ± 17.38 |
49.81 ± 15.76 |
p = 0.029 |
|
LV untwisting rate (o/s) |
-80.44 ± 26.23 |
-58.34 ± 31.1 |
p = 0.040 |
|
BASE |
|
|
|
|
Rotation (o) |
-5.25 ± 1.50 |
-4.14 ± 1.63 |
p = 0.040 |
|
Peak systolic rotation rate (o/s) |
-43.08 ± 16.37 |
-38.57 ± 12.07 |
NS |
|
Peak radial strain |
40.33 ± 13.37 |
36.03 ± 12.03 |
NS |
|
Peak systolic circumferential strain |
-12.18 ± 3.77 |
-10.49 ± 2.75 |
p = 0.023 |
|
APEX |
|
|
|
|
Rotation (o) |
3.71 ± 1.77 |
2.41 ± 2.73 |
NS |
|
Peak systolic rotation rate (o/s) |
30.63 ± 13.01 |
19.36 ± 23.61 |
NS |
|
Peak radial strain |
39.5 ± 10.77 |
27.81 ± 12.89 |
p = 0.005 |
|
Peak systolic circumferential strain |
-15.07 ± 4.71 |
-12.38 ± 2.43 |
p = 0.020 |
LV Twist (0): peak difference in systolic rotations of LV apex and base as viewed from the apex, LV Torsion (0/cm): normalized twist: twist angle divided by the distance between the measured locations of base and apex, LV Systolic Torsion Rate (0/s): peak velocity of LV Torsion, LV Untwisting Rate (0/s): peak velocity of Untwisting, Rotation (0): peak systolic Rotation of base or apex, Peak Systolic Rotation Rate (0/s): peak velocity of basal or apical Rotation, Peak Radial Strain: peak radial deformation of base or apex, Peak Systolic Circumferential Strain: circumferential deformation of base or apex.
The values are averages ± standard deviation.