Table 1: Effect of esmolol on the hemodynamic and conventional variables in intact myocardium.
|
Control |
ESMOLOL |
p |
|
|
EDV (ml) |
63.53 ± 9.01 |
61.08 ± 11.08 |
NS |
|
ESV (ml) |
30.25 ± 5.95 |
37.88 ± 8.97 |
p = 0.005 |
|
SV (ml) |
33.30 ± 4.86 |
23.10 ± 6.40 |
p < 0,001 |
|
EF (%) |
51.60 ± 5.03 |
38.15 ± 8.80 |
p < 0.001 |
|
CO (ml/min) |
3094.40 ± 570.37 |
2171.85 ± 515.25 |
p < 0.001 |
|
LVSP (mmHg) |
95.35 ± 11.96 |
85.34 ± 13.47 |
p < 0.001 |
|
LV dP/dtmax (mmHg/s) |
1.36 ± 0.31 |
1.03 ± 0.38 |
p < 0.001 |
|
HR (beats/min) |
94.08 ± 17.91 |
96.88 ± 17.78 |
NS |
|
E/e΄ ratio |
8.15 ± 4.22 |
8.91 ± 3.00 |
NS |
EDV: LV End-Diastolic Volume (ml), ESV: LV End-Systolic Volume (ml), SV: LV Stroke Volume (ml), EF: LV Ejection Fraction (%), CO: Cardiac Output (ml/min), LVSP: LV End-Systolic Pressure (mmHg), LV dP/dtmax: the maximal rate of rise of LV Pressure according to time (mmHg/s), HR: Heart rate (beats/min), E: mitral early filling velocity (m/s), e´: early diastolic mitral annulus velocity by tissue Doppler imaging, E/e´: ratio of two velocities.
The values are averages ± standard deviation.