Action of Antioxidants

Action of CBD

Donate electron to molecules with unpaired electron

Antagonist to CB1R and agonist to CB2R

Activate ROS-resistant Nrf2

Elevates anandamide which acts as an agonist to CB1R and CB2R

Enhance the expression of microRNAs

Acts as an agonist to dopamine, serotonin, and adenosine receptors

Alter gene expression

Acts as an antagonist to glutamate Receptors

Reduce release and toxicity of glutamate

Activates PPAR-gamma

Reduce pro-inflammatory cytokines

Acts as an inhibitor of serotonin-re-uptake

Increases expression of genes coding for anti-inflammatory cytokines

Activates NGF receptor

Week antioxidant and ant-inflammation activities