Gene Set Name

# Genes in Gene Set (K)

# Genes in Overlap (k)

k/K

p-value

FDR q-value

REACTOME_IMMUNE_SYSTEM

933

72

0.077

9.41E-12

6.34E-09

REACTOME_SIGNALING_BY_GPCR

920

65

0.071

3.38E-09

1.14E-06

REACTOME_GPCR_DOWNSTREAM_SIGNALING

805

58

0.072

1.18E-08

2.66E-06

REACTOME_ADAPTIVE_IMMUNE_SYSTEM

539

43

0.080

5.58E-08

9.40E-06

REACTOME_HEMOSTASIS

466

37

0.079

5.16E-07

6.96E-05

REACTOME_DEVELOPMENTAL_BIOLOGY

396

32

0.081

2.04E-06

2.29E-04

REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS

478

35

0.073

6.30E-06

5.73E-04

REACTOME_CELL_CYCLE

421

32

0.076

7.28E-06

5.73E-04

REACTOME_SIGNALLING_BY_NGF

217

21

0.097

7.65E-06

5.73E-04

REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION

91

12

0.132

3.39E-05

2.28E-03

REACTOME_CELL_CYCLE_MITOTIC

325

25

0.077

5.74E-05

3.52E-03

REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING

24

6

0.250

8.73E-05

4.90E-03

REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

72

10

0.139

9.67E-05

5.01E-03

REACTOME_G_ALPHA1213_SIGNALLING_EVENTS

74

10

0.135

1.22E-04

5.89E-03

REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION

212

18

0.085

1.80E-04

7.56E-03

REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES

413

28

0.068

1.88E-04

7.56E-03

REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

251

20

0.080

1.91E-04

7.56E-03

REACTOME_P75_NTR_RECEPTOR_MEDIATED_SIGNALLING

81

10

0.124

2.61E-04

9.79E-03

REACTOME_GPCR_LIGAND_BINDING

408

27

0.066

3.54E-04

1.26E-02

REACTOME_PHASE1_FUNCTIONALIZATION_OF_COMPOUNDS

70

9

0.129

3.87E-04

1.30E-02

REACTOME_OLFACTORY_SIGNALING_PATHWAY

328

23

0.070

4.23E-04

1.30E-02

REACTOME_METABOLISM_OF_CARBOHYDRATES

247

19

0.077

4.23E-04

1.30E-02

REACTOME_SIGNALING_BY_NOTCH

103

11

0.107

4.71E-04

1.38E-02

REACTOME_AXON_GUIDANCE

251

19

0.076

5.16E-04

1.45E-02

REACTOME_SIGNALING_BY_ILS

107

11

0.103

6.51E-04

1.76E-02

REACTOME_INNATE_IMMUNE_SYSTEM

279

20

0.072

7.41E-04

1.85E-02

REACTOME_NEURONAL_SYSTEM

279

20

0.072

7.41E-04

1.85E-02

REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

200

16

0.080

7.67E-04

1.85E-02

REACTOME_PLATELET_HOMEOSTASIS

78

9

0.115

8.64E-04

1.97E-02

REACTOME_COSTIMULATION_BY_THE_CD28_FAMILY

63

8

0.127

8.78E-04

1.97E-02

REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE

51

7

0.137

1.15E-03

2.49E-02

REACTOME_MEIOSIS

116

11

0.095

1.27E-03

2.69E-02

REACTOME_PLATELET_SENSITIZATION_BY_LDL

16

4

0.250

1.40E-03

2.77E-02

REACTOME_XENOBIOTICS

16

4

0.250

1.40E-03

2.77E-02

REACTOME_STRIATED_MUSCLE_CONTRACTION

27

5

0.185

1.50E-03

2.88E-02

REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE

137

12

0.088

1.56E-03

2.92E-02

REACTOME_GLUCOSE_METABOLISM

69

8

0.116

1.60E-03

2.92E-02

REACTOME_LIPOPROTEIN_METABOLISM

28

5

0.179

1.77E-03

3.15E-02

REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION

122

11

0.090

1.91E-03

3.31E-02

REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK

43

6

0.140

2.36E-03

3.97E-02

REACTOME_GENERIC_TRANSCRIPTION_PATHWAY

352

22

0.063

2.42E-03

3.99E-02

REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

44

6

0.136

2.65E-03

4.26E-02

REACTOME_CELL_DEATH_SIGNALLING_VIA_NRAGE_NRIF_AND_NADE

60

7

0.117

2.99E-03

4.68E-02

REACTOME_DNA_REPAIR

112

10

0.089

3.24E-03

4.97E-02

REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS

10

3

0.300

3.32E-03

4.97E-02