Table 1: Pain variables assessed after injection of hypertonic saline solution (58.5 mg/mL) into the masseter muscle of healthy participants. The men received an injection of 0.5 ml and the women 0.3 ml. Variables are presented as median (interquartile range).

    Pain measures

    Men

    (n=25)

    Women (n=31)

    P-value

    Max pain intensity (VAS 0-100)

    68.0 (34.0)

    84.0 (31.5)

    0.171

    Pain duration (s)

    300 (7.5)

    255 (180)

    <0.001

    AUC (au)

    251100 (266400)

    133800 (184200)

    0.005

    Pain after 300s (n)

    19

    9

    <0.001

    Pain intensity at 300 s

    14.0 (54.0)

    0 (1.0)

    <0.001

    Pain unpleasantness (VAS 0-100)

    69.0 (39.5)

    75.0 (46.0)

    0.786

    Anxiety (VAS 0-100)

    26.0 (64.5)

    23.0 (53.0)

    0.649

    Pain drawing area (Pixel)

    20355 (36341)

    18327 (16320)

    0.856

    N=number of subjects, AUC = area under the curve, VAS = visual analogue scale