Table 1: Examples for cytotoxic and non-cytotoxic members of the RNase A superfamily.
Toxicity |
RNase |
Source |
toxic |
BS-RNase |
bovine seminal fluid |
toxic |
ONC |
Rana pipiens |
toxic |
sialic acid binding lectin (SBL-J / RJL) |
Rana japonica |
toxic |
sialic acid binding lectin (SBL-C / RCL) |
Rana catesbeiana |
toxic |
Amph 1-4 |
Rana pipens |
non-toxic |
RNase A |
bovine pancreas |
non-toxic |
RNase 1 |
human pancreas |
non-toxic |
eosinophil-derived neurotoxin (EDN) |
human eosinophils |
non-toxic |
angiogenin (ANG) |
human serum |