Table 1: Examples for cytotoxic and non-cytotoxic members of the RNase A superfamily.

Toxicity

RNase

Source

toxic

BS-RNase

bovine seminal fluid

toxic

ONC

Rana pipiens

toxic

sialic acid binding lectin (SBL-J / RJL)

Rana japonica

toxic

sialic acid binding lectin (SBL-C / RCL)

Rana catesbeiana

toxic

Amph 1-4

Rana pipens

non-toxic

RNase A

bovine pancreas

non-toxic

RNase 1

human pancreas

non-toxic

eosinophil-derived neurotoxin (EDN)

human eosinophils

non-toxic

angiogenin (ANG)

human serum