Table 1: Clinical course of the patient.

No. of attempt

OS methods

 Pre-ovulatory

Trigger

Kinds of  treatment

Pregnancy

Adverse effect

 

 

 

 

follicle development

 

 

 

 

 

 

 

1

CC 100 mg/day for 5 days

Right side, 18 mm

HCG 5000IU

TSIa) at WDB16

no

mild OHSS***

2

CC 100 mg/day for 5 days

Follicular growth (-)

non

non

no

no

3

CC 150 mg/day for 5 days

Follicular growth (-)

non

non

no

no

4

FSH 150 IU/day for 11days

Total of 7-8  development follicles

no

Severe OHSS***

Both sides,  19-18 mm size at WDB13

HCG 5000IU

TSIa) at WDB15

5

FSH 75 IU/day for 8 days,

FSH 150 IU/day for 8 days, and

FSH 300 IU/day for 8 days

Follicular growth (-)

non

non

no

no

6

Letrozole 25 mg/day for 10 days

Left side, 19 mm

HCG 5000IU

TSI* at WDB21

no

no

7~11

Letrozole 25 mg/day plus

Development follicles (1–2)

FSH 150 IU/day  for 7-8days

Right or Left 20–19 mm size

Gn-RH agonist

IUI** at D14-15

no

no

11

Letrozole 25 mg/day plus

Right side, 21 mm

Gn-RH agonist

IUI** at D14

yes

no

 

 FSH 150 IU/day  for 7 days

 

 

 

 

 

 

 

 

 

a)Timed sexual intercourse. b) Intrauterine insemination. c) Ovarian hyperstimulation syndrome.

1) Ovarian stimulation was started from WDB 5 until third attempt and started from WDB 3 after fourth attempt.

2) CC, FSH, and letrozole were administered every day.