Table 3: Patients with long-term survival.
|
Case 1 |
Case 2 |
Case 3 |
Case 4 |
Case 5 |
|
|
gender |
male |
male |
female |
male |
male |
|
age |
19 |
24 |
24 |
30 |
48 |
|
main complain |
fatigue |
fever |
Fever, lymph node enlargement |
fatigue |
recurrent abdominal pain |
|
WBC(/L) |
102.77×109 |
71.4×109 |
107.73×109 |
4.03×109 |
27.8×109 |
|
Hb(g/L) |
60 |
125 |
61 |
86 |
93 |
|
PLT(/L) |
59×109 |
230×109 |
56×109 |
37×109 |
106×109 |
|
marrow blast |
94% |
71.5% |
77% |
90.4% |
95.5% |
|
Flow
cytometry analysis |
CD58,CD66,CD34,CD10,CD19,CD45 |
HLA-DR,CD10,CD19,CD20,CD22,CD38,CD123,CD79a,TdT |
CD19,CD10,CD33,CD38,CD22,CD79a,HLA-DR |
CD79a,CD22,CD19,CD10, |
CD34,CD79a,
CD19,CD10 |
|
chromosome |
41-46,XY,9P-[CP7]/45,XY,9P-/46,XY |
46,XY,t(9,22)(q34;q11.2) |
47,XX,t(1:11)(p36.1:q21),+21[8]/46,XX[1] |
44,XY,-7,t(9;22)(q34;q11),-13[15]/46,XY[5] |
46,XY,t(9,22)(q34;q11.2) |
|
gene |
BCR/ABL(p210) |
BCR/ABL(p190) |
BCR/ABL |
||
|
induction therapy |
VDCLP |
VDCP+ dasatinib |
VDCLP |
hyper-CVAD+ imatinib |
VDCLP+ dasatinib |
|
HSCT |
umbilical
cord blood transplantation was performed 4.5 months after diagnosis during
CR1 |
allo-HSCT
was performed 5 months after diagnosis during CR1 |
allo-HSCT
was performed 3 months after diagnosis during CR1 |
allo-HSCT
was performed 4.5 months after diagnosis during CR1 |
allo-HSCT
was performed 4.5 months after diagnosis during CR1 |